Name: Advances in Host-Directed Therapies Against Tuberculosis (en Inglés)
Price: 366100.00 CLP
Availability: InStock
Author: Karakousis, Petros C. ; Hafner, Richard ; Gennaro, Maria Laura
ISBN: 9783030569075

portada Advances in Host-Directed Therapies Against Tuberculosis (en Inglés)

Formato

Libro Físico

Editorial

Springer

Autor

Karakousis, Petros C. ; Hafner, Richard ; Gennaro, Maria Laura

Idioma

Inglés

N° páginas

332

Encuadernación

Tapa Blanda

Dimensiones

23.4 x 15.6 x 1.8 cm

Peso

0.49 kg.

ISBN13

9783030569075

Categorías

Enfermedades infectocontagiosas
Inmunología
Farmacología

Advances in Host-Directed Therapies Against Tuberculosis (en Inglés)

Karakousis, Petros C. ; Hafner, Richard ; Gennaro, Maria Laura (Autor) · Springer · Tapa Blanda

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Reseña del libro "Advances in Host-Directed Therapies Against Tuberculosis (en Inglés)"

This book discusses specific immune cell regulatory pathway(s), immune cell types, or other mechanisms involved in host responses to tuberculosis that can be potentially targeted for host-directed therapy (HDT). The pathways/mechanisms investigated are either protective - thus calling for pathway/factor enhancing drugs - or maladaptive - thus calling for pathway/factor inhibitory drugs. Discovery and development (pre-clinical and clinical) of candidate HDT agents will also be elucidated, as well as approaches for HDT of other diseases. The benefit to the reader will derive from learning about the biology of multiple host pathways involved in health and disease, how these pathways are disrupted or dysregulated during tuberculosis, and which druggable targets exist in these pathways. This book provides the reader with a roadmap of current and future directions of HDT against tuberculosis. Since the host pathways/factors involved in protective or maladaptive responses to tuberculosis are not disease-specific, information learned from the context of tuberculosis likely will be relevant to other infectious and non-infectious diseases.