Name: Comprehensive Biomarker Discovery and Validation for Clinical Application (Drug Discovery) (en Inglés)
Price: 276010.00 CLP
Availability: InStock
Author: Peter Horvatovich
ISBN: 9781849734226

portada Comprehensive Biomarker Discovery and Validation for Clinical Application (Drug Discovery) (en Inglés)

Formato

Libro Físico

Editorial

Royal Society Of Chemistry

Autor

Peter Horvatovich

Año

2013

Idioma

Inglés

N° páginas

384

Encuadernación

Tapa Dura

ISBN

1849734224

ISBN13

9781849734226

N° edición

Categorías

Medicina general y de familia

Comprehensive Biomarker Discovery and Validation for Clinical Application (Drug Discovery) (en Inglés)

Peter Horvatovich (Autor) · Royal Society Of Chemistry · Tapa Dura

Libro Físico

$ 276.010

$ 460.010

Ahorras: $ 184.000

40% descuento

Envío normal

Origen: Reino Unido (Costos de importación incluídos en el precio)

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Reseña del libro "Comprehensive Biomarker Discovery and Validation for Clinical Application (Drug Discovery) (en Inglés)"

Comprehensive Biomarker Discovery and Validation for Clinical Application provides the reader with an extensive introduction into all aspects of proteomics biomarker discovery, validation and development. It discusses the current status of science and technology, its limitations, bottlenecks as well as future development trends to improve the success rate of translating biomarker discovery into useful clinical tests. The most important feature of the book is to provide an overview of current technologies and the challenges encountered during biomarker discovery and validation, such as patient selection, sample handling, data processing, statistical analysis and registration and approval of validated biomarkers through European and US regulatory authorities. The authors introduce the reader to each of these topics in significant detail and provide examples or guidelines for best practice. There are prominent chapters included on biomarkers in translational and personalised medicine; an introduction to regulatory affairs and bring biomarkers to the market; biomarker discovery and the use of mass spectrometry based profiling platforms; MALDI imaging techniques in tissue-based biomarkers discovery and a clinical application study on the use of diagnostic assays for early diagnosis of heart failure using various proteomic methods. The book concludes with a final chapter on future trends in biomarker discovery and validation. The book targets a readership of industrial and academic researchers that are involved in biomarker discovery and validation or that manage biobanks, develop sample preparation methods, analytical profiling systems and bioinformatics tools. Common pitfalls and success stories in biomarker discovery are highlighted and guidelines for best practice are provided for the different parts of the procedure. The book will be an essential information resource for scientists working in the field.