Name: Effects of cigarette components on the DNA molecule (en Inglés)
Price: 41900.00 CLP
Availability: InStock
Author: Queiroz, Paulo Roberto ; M. O. Paulucio, Fernanda ; A. Foschete, Cláudia
ISBN: 9786207329670

portada Effects of cigarette components on the DNA molecule (en Inglés)

Formato

Libro Físico

Autor

Paulo Roberto Queiroz

Fernanda M. O. Paulucio

Cláudia A. Foschete

Editorial

Our Knowledge Publishing

Idioma

Inglés

N° páginas

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.3 cm

Peso

0.09 kg.

ISBN13

9786207329670

Categorías

Genética (no médica)

Effects of cigarette components on the DNA molecule (en Inglés)

Paulo Roberto Queiroz (Autor) · Fernanda M. O. Paulucio (Autor) · Cláudia A. Foschete (Autor) · Our Knowledge Publishing · Tapa Blanda

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Envío normal

Origen: Estados Unidos (Costos de importación incluídos en el precio)

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Reseña del libro "Effects of cigarette components on the DNA molecule (en Inglés)"

Smoking control is one of the biggest challenges for public health promotion, as it is responsible for high mortality rates which could be avoided. Studies show that the components derived from cigarette combustion cause epigenetic changes, such as methylation of the DNA molecule. This alteration causes gene silencing, resulting in a lack of gene expression and contributing to the phenotypic expression of various diseases, especially cancers, cardiovascular and lung diseases. Telomeres, on the other hand, are DNA-protein complexes that promote genome stability. They are located at the ends of eukaryotic chromosomes and in humans are represented by repetitive sequences of 6 nucleotides (TTAGGG)n. Telomere shortening occurs with each cell replication and this reduction leads to cellular senescence and apoptosis. Oxidative stress is one of the factors that accelerates telomere shortening and tobacco smoking contributes to this stress. Studies show a clear correlation between tobacco consumption, oxidative stress, early telomere shortening and inadequate DNA methylation.