Name: Formulation and In-Vitro Evaluation of Floating Tablet of Gabapentin (en Inglés)
Price: 94650.00 CLP
Availability: InStock
Author: Kar, Nihar Ranjan ; Mahapatra, Santosh Kumar ; Pothal, Rajesh Kumar
ISBN: 9786203846461

portada Formulation and In-Vitro Evaluation of Floating Tablet of Gabapentin (en Inglés)

Formato

Libro Físico

Autor

Nihar Ranjan Kar

Santosh Kumar Mahapatra

Rajesh Kumar Pothal

Editorial

LAP Lambert Academic Publishing

Idioma

Inglés

N° páginas

112

Encuadernación

Tapa Blanda

Dimensiones

22.9 x 15.2 x 0.7 cm

Peso

0.18 kg.

ISBN13

9786203846461

Categorías

Farmacología

Formulation and In-Vitro Evaluation of Floating Tablet of Gabapentin (en Inglés)

Nihar Ranjan Kar (Autor) · Santosh Kumar Mahapatra (Autor) · Rajesh Kumar Pothal (Autor) · LAP Lambert Academic Publishing · Tapa Blanda

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Reseña del libro "Formulation and In-Vitro Evaluation of Floating Tablet of Gabapentin (en Inglés)"

The present research work is an attempt to formulate rate controlled drug delivery system of Gabapentin which is primarily absorbed from stomach, so by increasing the GRT of the drug, the bioavailability can be increased. As the drug is stable in acidic pH and mostly absorbed with in pH 1-3, as the stomach is the major absorption site for the drug. Basing on this fact the drug is made to float in the stomach using the mechanism of buoyancy. The study also includes various evaluation studies of Gabapentin tablet and the effect of processing variables on it. A possible interaction between drug and polymers are also investigated by FTIR and DSC studies. So, the present work has been under taken with the objective of designing and evaluation of floating oral sustained release tablet drug delivery system of Gabapentin by using HPMC K15, NaCMC, Xanthun gum, sodium bicarbonate, citric acid. Lactose, ethyl cellulose etc.