Name: Reactive Sulfur Species in Biology and Medicine (en Inglés)
Price: 93540.00 CLP
Availability: InStock
Author: Toscano, John P. ; Khodade, Vinayak S.
ISBN: 9783036591209

portada Reactive Sulfur Species in Biology and Medicine (en Inglés)

Formato

Libro Físico

Editorial

Mdpi AG

Autor

Toscano, John P. ; Khodade, Vinayak S.

Idioma

Inglés

N° páginas

210

Encuadernación

Tapa Dura

Dimensiones

24.4 x 17.0 x 1.8 cm

Peso

0.65 kg.

ISBN13

9783036591209

Categorías

Farmacología
Biología

Reactive Sulfur Species in Biology and Medicine (en Inglés)

Toscano, John P. ; Khodade, Vinayak S. (Autor) · Mdpi AG · Tapa Dura

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Reseña del libro "Reactive Sulfur Species in Biology and Medicine (en Inglés)"

Hydrogen sulfide (H2S) is a naturally occurring signaling molecule produced in vivo and plays a pivotal role in regulating a wide array of physiological processes. Additionally, emerging findings have illuminated that many of the biological effects initially attributed to H2S may actually stem from other reactive sulfur species (RSS), including hydropersulfides (RSSH) and various higher-order polysulfur species (RSSnH, RSSnR, and HSnH, where n > 1). These studies have underscored the contributions of these species to essential cellular processes, such as the efficient scavenging of reactive oxygen species and electrophiles, and their influence on mitochondrial function. Nonetheless, the chemistry of RSS remains challenging due to their inherently reactive nature, and their precise measurement within biological systems continues to pose a formidable challenge. This compilation of reprints focuses on recent advancements in the field of H2S/RSS chemical biology. It encompasses original research studies and comprehensive reviews, all geared towards exploring the therapeutic potential of H2S/RSS donors in the treatment of various conditions, including cancer, neurological disorders, and cardiovascular disease. Furthermore, it delves into the molecular mechanisms and physiological roles played by RSS along with the development of methodologies for quantifying and measuring the distribution of RSS within biological systems.